Case Reports (References)

27 July 2022

Ortiz-Martínez Y, Rodríguez-Morales AJ, Franco-Paredes C, et al. Monkeypox – a description of the clinical progression of skin lesions: a case report from Colorado, USA. Ther Adv Infect Dis. 2022 Jul 27;9:20499361221117726. PubMed: Full text:

“Skin lesions caused by MPXV are susceptible to bacterial superinfection, and strict follow-up of patients is necessary, even in mild or moderate forms. Clinicians should have a high index of suspicion for any atypical genital lesions in the right epidemiologic setting.”


Pembi E, Awang S, Salaudeen SO, Agaba IA, Omoleke S. First confirmed case of monkeypox in Adamawa State, Nigeria: a clinico-epidemiological case report. Pan Afr Med J. 2022 May 16;42:38. PubMed: Full text:

“The patient was also found reactive for syphilis when evaluated at the 23 BMC Yola before his referral to FMC Yola on account of secondary syphilis. Syphilis mimics monkeypox in its clinical manifestation of fever, sore throat, headaches, swollen lymph glands, muscle aches, skin rashes and/or mucous membrane lesions. However, patchy hair loss, painless chancre and weight loss that often occurs in syphilis are not seen in monkeypox.”


26 July 2022

Ajmera KM, Goyal L, Pandit T, Pandit R. Monkeypox – An emerging pandemic. IDCases. 2022 Jul 26;29:e01587. PubMed: Full text:

A 26-year-old polygamous, homosexual man with a past medical history of syphilis and on tenofovir/emtricitabine for HIV pre-exposure prophylaxis (PrEP) with a progressively worsening rash on his tongue and around the mouth.


11 July 2022

Noe S, Zange S, Seilmaier M, et al. Clinical and virological features of first human monkeypox cases in Germany. Infection. 2022 Jul 11. PubMed: Full text:

The authors present clinical and virological findings of the first two cases of MPX infection in humans diagnosed in Germany, including the detection of monkeypox virus DNA in blood and semen. They assume that close physical contact during sexual interactions was the route of infection.


11 July 2022

Jang YR, Lee M, Shin H, et al. The First Case of Monkeypox in the Republic of Korea. J Korean Med Sci. 2022 Jul 11;37(27):e224. PubMed: Full text:

Monkeypox in a in a 34-year-old male patient from South Korea who traveled to Europe in June 2022.


6 July 2022

Sukhdeo SS, Aldhaheri K, Lam PW, Walmsley S. A case of human monkeypox in Canada. CMAJ. 2022 Jul 6:cmaj.220886. PubMed: Full text:

Twelve days after unprotected, receptive orogenital and oroanal intercourse with a new, anonymous male partner, the patient described in this report developed enlarged, painful, tender inguinal and cervical lymphadenopathy, chills and night sweats. One day later, he developed rectal pain and tenesmus, followed by the appearance of 4 pruritic, painless macules on his forearm and wrist on day 15, which became vesicular and then pustular over the subsequent 7 days.


28 June 2022

Ogoina D, Mohammed A, Yinka-Ogunleye A, Ihekweazu C. A case of suicide during the 2017 monkeypox outbreak in Nigeria. IJID Reg. 2022 Apr 25;3:226-227. PubMed: Full text: eCollection 2022 Jun

To the knowledge of the authors, “this is the first reported case of suicide linked to human monkeypox.”


4 June 2022

Hammerschlag Y, MacLeod G, Papadakis G, et al. Monkeypox infection presenting as genital rash, Australia, May 2022. Euro Surveill. 2022 Jun;27(22):2200411. PubMed: Full text:

“Classical descriptions of monkeypox depict patients initially presenting with a fever and systemic symptoms followed by a rash that is most commonly monomorphic with a centrifugal distribution (concentrated on face and distal extremities). The initial presentation of a penile rash in our patient suggests close physical contact during sexual contact as the route of acquisition.”


8 April 2022

Rao AK, Schulte J, Chen TH, et al. Monkeypox in a Traveler Returning from Nigeria – Dallas, Texas, July 2021. MMWR Morb Mortal Wkly Rep. 2022 Apr 8;71(14):509-516. PubMed: Full text:

Case report of a man who in July 2021 traveled from Lagos, Nigeria, to Dallas, Texas, US. Among 194 monitored contacts, 144 (74%) were flight contacts. No secondary cases occurred.


9 March 2022

Costello V, Sowash M, Gaur A, et al. Imported Monkeypox from International Traveler, Maryland, USA, 2021. Emerg Infect Dis. 2022 May;28(5):1002-1005. PubMed: Full text:

A case of monkeypox was diagnosed in a returning traveler from Nigeria to Maryland, USA. No secondary cases in 40 exposed healthcare workers. “Multiple appearances beyond disease-endemic countries indicate that monkeypox has become a relevant travel-related disease, and physicians should remain vigilant in combatting transmission of this virus.”


15 November 2004

Sejvar JJ, Chowdary Y, Schomogyi M, et al. Human monkeypox infection: a family cluster in the midwestern United States. J Infect Dis. 2004 Nov 15;190(10):1833-40. PubMed: Full text:

Of 3 family members with monkeypox, 2 had rash illness only, and 1 required hospitalization for severe encephalitis. The family member with the mildest clinical course had previously received smallpox vaccination.